Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478359 | 0.93 | ITGB3 (0.46) | ITGB3ITGA2BSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7361345 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7471266 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7472139 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7470113 | 0.83 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL7468977 | 0.83 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL7469311 | 0.82 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7472244 | 0.81 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7464123 | 0.81 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL7468256 | 0.79 | ITGB3 (0.66) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852225-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND MEDICINAL PREPARATIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | NIPPON STEEL CORP (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0852225-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND MEDICINAL PREPARATIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | NIPPON STEEL CORPORATION (JP) | 1998-07-08 | — | — | EP | disclosed |