Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177133 | 0.76 | ITGB2 (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL6344023 | 0.69 | SMN1; SMN2 (0.33) | ITGB2ICAM1ITGAL | |
| SCHEMBL9192352 | 0.68 | — | — | |
| SCHEMBL6350747 | 0.67 | KDM4E (0.35) | ITGB2ICAM1ITGAL | |
| SCHEMBL6350809 | 0.67 | CTNNB1 (0.37) | — | |
| SCHEMBL6342500 | 0.66 | PDCD1 (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL7468599 | 0.65 | MEN1 (0.38) | — | |
| SCHEMBL9054579 | 0.65 | MAPT (0.41) | — | |
| SCHEMBL5845932 | 0.65 | LMNA (0.42) | — | |
| SCHEMBL6668879 | 0.65 | MAP3K14 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977749-B1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-03-13 | — | — | EP | disclosed |
| EP-0977749-A1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998056783-A1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1998-12-17 | — | — | WO | disclosed |