SCHEMBL7473838

SCHEMBL7473838

CCOC(=O)Oc1scc(Cl)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 2/20 0.39
ALDH1A1 P00352 7/20 0.38
PRKCZ Q05513 4/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
POLB P06746 1/20 0.35
SOAT1 P35610 1/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 1/20 0.34
GRM6 O15303 1/20 0.34
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7477548 0.98 ALDH1A1 (0.40) CUL4AALDH1A1PRKCZMAPK1KDM4E
SCHEMBL7471159 0.84 ALDH1A1 (0.40) ALDH1A1PRKCZMAPK1KDM4EMAPT
Hydrochloric Acid SCHEMBL7475720 0.83 ALDH1A1 (0.42) ALDH1A1PRKCZMAPK1KDM4EL3MBTL1
SCHEMBL7471816 0.83 ALDH1A1 (0.41) ALDH1A1PRKCZMAPK1MAPTMEN1
SCHEMBL5240020 0.82 CUL4A (0.35) CUL4AALDH1A1PRKCZKDM4EKMT2A
Hydrochloric Acid SCHEMBL7473300 0.81 ALDH1A1 (0.41) ALDH1A1PRKCZMAPK1KDM4EL3MBTL1
SCHEMBL7476334 0.78 MAPT (0.32) ALDH1A1PRKCZMAPTMEN1KMT2A
SCHEMBL7466379 0.78 MAPK8 (0.36) ALDH1A1PRKCZMAPK1KDM4EMAPT
Hydrochloric Acid SCHEMBL7471525 0.77 MAPT (0.31) ALDH1A1PRKCZMAPTPOLB
Hydrochloric Acid SCHEMBL7462256 0.77 ALDH1A1 (0.38) ALDH1A1PRKCZMAPK1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed