Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 5/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7467353 | 0.89 | MAPT (0.53) | HRASESR1ESR2TOP1MAPT | |
| SCHEMBL7465939 | 0.84 | MAPT (0.43) | HRASESR1ESR2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL7462715 | 0.83 | MAPT (0.42) | HRASESR1ESR2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7471319 | 0.82 | HRAS (0.48) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7466531 | 0.82 | MAPT (0.47) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7472116 | 0.81 | HRAS (0.42) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7470286 | 0.81 | HRAS (0.40) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7471330 | 0.77 | HRAS (0.55) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7475008 | 0.77 | HRAS (0.64) | HRASESR1ESR2TOP1MAPT | |
| Hydrochloric Acid SCHEMBL7465502 | 0.77 | HRAS (0.58) | HRASESR1ESR2TOP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |