Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HRAS | P01112 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7462715 | 0.99 | MAPT (0.42) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7471355 | 0.87 | MAPT (0.43) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7473157 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7470258 | 0.84 | HPGD (0.46) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7474162 | 0.84 | HRAS (0.41) | MAPTPOLBHRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7466054 | 0.84 | FLT3 (0.38) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7477278 | 0.83 | MAPT (0.42) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8987620 | 0.83 | CHEK2 (0.50) | MAPTPOLBL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7467353 | 0.82 | MAPT (0.53) | MAPTPOLBHRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL8987691 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2AL3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |