Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474389 | 0.91 | AVPR2 (0.33) | AVPR2AVPR1AMEN1KMT2AUSP2 | |
| SCHEMBL7479773 | 0.91 | AVPR2 (0.32) | AVPR2AVPR1AMEN1KMT2AUSP2 | |
| SCHEMBL7475353 | 0.84 | MEN1 (0.35) | AVPR2AVPR1ACBX7MEN1KMT2A | |
| SCHEMBL7953703 | 0.84 | AVPR2 (0.39) | AVPR2AVPR1A | |
| SCHEMBL7479769 | 0.84 | — | — | |
| SCHEMBL7476546 | 0.83 | MEN1 (0.34) | AVPR2AVPR1ACBX7MEN1KMT2A | |
| SCHEMBL7478475 | 0.83 | CBX7 (0.38) | AVPR2AVPR1ACBX7MEN1KMT2A | |
| SCHEMBL7781332 | 0.81 | KMT2A (0.39) | AVPR2AVPR1ACBX7MEN1KMT2A | |
| SCHEMBL7340721 | 0.80 | AVPR2 (0.39) | AVPR2AVPR1ACBX7MEN1KMT2A | |
| SCHEMBL7476401 | 0.80 | MEN1 (0.35) | AVPR2AVPR1ACBX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |