Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478475 | 0.91 | CBX7 (0.38) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7340721 | 0.89 | AVPR2 (0.39) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7476401 | 0.87 | MEN1 (0.35) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8637529 | 0.86 | AVPR2 (0.40) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7962078 | 0.84 | RAB9A (0.35) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7486482 | 0.84 | RAB9A (0.35) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7972227 | 0.84 | BDKRB2 (0.34) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7482468 | 0.84 | RAB9A (0.35) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7473879 | 0.83 | AVPR2 (0.34) | KMT2AHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7778599 | 0.83 | SIGMAR1 (0.37) | KMT2AMEN1ALDH1A1POLBAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |