⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207838 | 0.96 | — | — | |
| SCHEMBL28142023 | 0.96 | ALDH1A1 (0.53) | — | |
| SCHEMBL1782947 | 0.96 | — | — | |
| SCHEMBL27479871 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28013651 | 0.93 | — | — | |
| SCHEMBL27655884 | 0.93 | — | — | |
| SCHEMBL10531490 | 0.92 | — | — | |
| SCHEMBL27573855 | 0.84 | — | — | |
| SCHEMBL11922808 | 0.69 | — | — | |
| SCHEMBL19686880 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286599-A | Synthetic method of sulfonamide compound containing benzodihydrofuran structure | 常州工程职业技术学院 | 2022-11-04 | — | — | CN | disclosed |
| US-7786149-B2 | Thiadiazoles as CXC- and CC- chemokine receptor ligands | SCHERING CORP. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7671212-B2 | Isothiazole dioxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080090823-A1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME CORP. | 2008-04-17 | — | — | US | disclosed |
| EP-0923562-B1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |
| EP-0215238-B1 | PROCESS FOR PURIFYING THIOCARBAMYLSULFENAMIDES | The B.F. GOODRICH Company (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4639517-A | Process for stabilizing thiocarbamylsulfenamides | THE B F GOODRICH COMPANY (US) | 1987-01-27 | — | — | US | disclosed |
| US-4632986-A | Process for purifying thiocarbamylsulfenamides | THE BFGOODRICH COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| US-3985743-A | FROM AN AMINE AND A MONOHALOAMINE WTIH CARBON DISULFIDE IN A BASE | THE B. F. GOODRICH COMPANY (US) | 1976-10-12 | — | — | US | disclosed |