Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 16/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590923 | 0.96 | CRHR1 (0.43) | CRHR1TSHRLMNA | |
| SCHEMBL8194048 | 0.88 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7483912 | 0.88 | CRHR1 (0.51) | CRHR1LMNA | |
| SCHEMBL7538831 | 0.84 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7480702 | 0.81 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL7625566 | 0.79 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL27500001 | 0.78 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7624865 | 0.76 | CRHR1 (0.46) | CRHR1TSHR | |
| SCHEMBL8202018 | 0.76 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7534738 | 0.74 | CRHR1 (0.49) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935601-A4 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARM CO (US) | 2002-08-07 | — | — | EP | claimed |
| EP-0935601-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | Du Pont Pharmaceuticals Company (US) | 1999-08-18 | — | — | EP | claimed |
| WO-1997035539-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | claimed |