Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | TCF7 | P36402 | 2/20 | 0.52 |
| ▸ | BCL9 | O00512 | 1/20 | 0.52 |
| ▸ | TCF4 | P15884 | 1/20 | 0.52 |
| ▸ | CLPP | Q16740 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745558 | 0.96 | CLPP (0.49) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747121 | 0.95 | CYP3A4 (0.48) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL10226398 | 0.94 | CYP3A4 (0.54) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL13757616 | 0.94 | CYP3A4 (0.52) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL744801 | 0.94 | CYP3A4 (0.52) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL764059 | 0.93 | CYP3A4 (0.52) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL12152953 | 0.93 | CYP3A4 (0.52) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL745999 | 0.93 | CYP3A4 (0.46) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL744497 | 0.93 | CYP3A4 (0.54) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL10267288 | 0.91 | CYP3A4 (0.51) | CYP3A4CTNNB1TCF4CLPPCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729262-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2014-05-20 | — | — | US | disclosed |
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8138337-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-03-20 | — | — | US | disclosed |
| US-8106049-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-31 | — | — | US | disclosed |
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-7932384-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-04-26 | — | — | US | disclosed |
| US-7671054-B1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-02 | — | — | US | disclosed |
| US-7585862-B2 | Colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss | CHOONGWAE PHARMA CORPORATION (KR) | 2009-09-08 | — | — | US | disclosed |
| US-7576084-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-08-18 | — | — | US | disclosed |
| US-7576084-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-08-18 | — | — | US | disclosed |
| US-7566711-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-07-28 | — | — | US | disclosed |
| US-7566711-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-07-28 | — | — | US | disclosed |
| US-7232822-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2007-06-19 | — | — | US | disclosed |