Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580205 | 0.93 | CTSK (0.50) | BTKMAP4K4CASRPDE10ACTSK | |
| SCHEMBL4580200 | 0.93 | CTSK (0.50) | BTKMAP4K4CASRPDE10ACTSK | |
| SCHEMBL15631969 | 0.90 | BTK (0.61) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL19657343 | 0.89 | CNR1 (0.55) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL12074150 | 0.89 | CNR1 (0.55) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL16544561 | 0.87 | MAP4K4 (0.52) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL16580814 | 0.87 | MAP4K4 (0.57) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL16434668 | 0.87 | MAP4K4 (0.52) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL22581878 | 0.87 | MAP4K4 (0.52) | BTKMAP4K4CA1CA2JAK3 | |
| SCHEMBL22581681 | 0.87 | BTK (0.56) | BTKMAP4K4CA1CA2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |