Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075781 | 0.88 | CRHR1 (0.67) | CRHR1CNR1 | |
| SCHEMBL7480024 | 0.85 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5417679 | 0.82 | CRHR1 (0.77) | CRHR1 | |
| SCHEMBL7472862 | 0.80 | CRHR1 (0.61) | CRHR1CNR1 | |
| SCHEMBL6075200 | 0.80 | CRHR1 (0.65) | CRHR1CNR1 | |
| SCHEMBL7474865 | 0.77 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL6203614 | 0.77 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7475228 | 0.77 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL14416720 | 0.76 | CRHR1 (0.76) | CRHR1 | |
| SCHEMBL7478434 | 0.76 | CRHR1 (0.66) | CRHR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | claimed |