Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899054 | 1.00 | SORD (0.49) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7900349 | 1.00 | SORD (0.49) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15345017 | 0.93 | SORD (0.51) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7467116 | 0.82 | KDM4E (0.51) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27810118 | 0.81 | KDM4E (0.53) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7897457 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL7469756 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL15344975 | 0.80 | SORD (0.48) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15345159 | 0.76 | SORD (0.52) | SORDKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7463955 | 0.75 | KDM4E (0.41) | SORDKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023273-B1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5HT1A RECEPTORS | PF MEDICAMENT (FR) | 2002-06-05 | — | — | EP | disclosed |
| US-6191130-B1 | HYPOTENSIVE AGENTS; THERAPY FOR SEXUAL DISORDERS; CENTRAL NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 2001-02-20 | — | — | US | disclosed |
| EP-1023273-A1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5T H1A RECEPTORS | PIERRE FABRE MEDICAMENT (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020613-A1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5T H1A RECEPTORS | PIERRE FABRE MEDICAMENT (FR) | 1999-04-29 | — | — | WO | disclosed |