Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724385 | 0.70 | ALDH1A1 (1.00) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL7479293 | 0.69 | ALDH1A1 (0.60) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL9565911 | 0.65 | ALDH1A1 (0.81) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL23269308 | 0.65 | HTT (0.74) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL23003 | 0.65 | TSHR (0.79) | ALDH1A1TSHRKMT2A | |
| SCHEMBL8595777 | 0.64 | POLB (0.87) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL10721777 | 0.64 | MEN1 (0.87) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL15347660 | 0.64 | ALDH1A1 (1.00) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL27629593 | 0.64 | KMT2A (0.71) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL28370887 | 0.64 | TSHR (0.76) | ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |