Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202546 | 0.89 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL5434392 | 0.87 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5437987 | 0.86 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5533554 | 0.86 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL5415379 | 0.85 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL6074526 | 0.84 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL5441012 | 0.84 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL5421186 | 0.84 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5434960 | 0.83 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL5434364 | 0.83 | CRHR1 (0.70) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | claimed |
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |