Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658354 | 0.78 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL10899341 | 0.76 | TDP1 (0.53) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL27800542 | 0.73 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL6984392 | 0.72 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL29097254 | 0.71 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL10599688 | 0.70 | TDP1 (0.46) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL16771568 | 0.69 | TDP1 (0.44) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| SCHEMBL18912895 | 0.69 | TSHR (0.77) | TDP1KMT2ASLC6A2SLC6A3TSHR | |
| Benzyl Benzoate SCHEMBL27990934 | 0.69 | KMT2A (0.92) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6402746 | 0.68 | TDP1 (0.59) | TDP1KMT2ASLC6A2SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120447-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-0889041-B1 | NOVEL IRIDOID DERIVATIVES AND NEOVASCULARIZATION INHIBITORS CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6225478-B1 | TREATMENT AND PREVENTION OF VARIOUS DISEASES ACCOMPANIED BY ABNORMAL ACCELERATION OF VASCULARIZATION, UNACCOMPANIED BY SERIOUS ADVERSE SIDE EFFECTS | TSUMURA & CO. (JP) | 2001-05-01 | — | — | US | disclosed |