Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054634 | 0.86 | MAPT (0.63) | MAPTTSHRHPGDALDH1A1TDP1 | |
| SCHEMBL7470399 | 0.84 | MAPT (0.61) | MAPTTSHRHPGDALDH1A1TDP1 | |
| SCHEMBL3060140 | 0.83 | MAPT (0.59) | MAPTTSHRHPGDALDH1A1TDP1 | |
| SCHEMBL3835000 | 0.82 | MAPT (0.67) | MAPTTSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL28907047 | 0.81 | ALDH1A1 (0.48) | MAPTTSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL7792084 | 0.80 | MAPT (0.55) | MAPTTSHRHPGDALDH1A1TDP1 | |
| SCHEMBL29740665 | 0.79 | MAPT (0.72) | MAPTTSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL5652170 | 0.78 | MAPT (0.61) | MAPTTSHRHPGDALDH1A1TDP1 | |
| SCHEMBL3059939 | 0.78 | MAPT (0.56) | MAPTTSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL3051207 | 0.77 | MAPT (0.52) | MAPTTSHRHPGDALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |