Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.42 |
| ▸ | THRA | P10827 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478245 | 0.83 | THRB (0.42) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7998508 | 0.79 | MEN1 (0.43) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7484859 | 0.76 | THRB (0.46) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL30586160 | 0.72 | THRB (0.41) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7989781 | 0.72 | THRB (0.48) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7998709 | 0.72 | THRB (0.43) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL8006662 | 0.71 | THRB (0.44) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7829095 | 0.71 | MEN1 (0.58) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7999085 | 0.70 | THRB (0.53) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL24780834 | 0.70 | THRB (0.49) | THRBTHRAMEN1NR1I2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | claimed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | claimed |
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |