Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108225 | 0.85 | ALDH1A1 (0.90) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL18026605 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL18026603 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL18029393 | 0.80 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL8288524 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL5970063 | 0.79 | HPGD (1.00) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL18029394 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL14140751 | 0.78 | HPGD (1.00) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL13486221 | 0.78 | HPGD (1.00) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL244547 | 0.78 | HPGD (1.00) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202968-A2 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010834-A9 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2001-08-09 | — | — | WO | disclosed |
| WO-2001010834-A2 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-02-15 | — | — | WO | disclosed |