Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046294 | 0.83 | HTR6 (0.43) | HTR2CHTR6SLC6A4HTR1ASLC6A2 | |
| SCHEMBL6046283 | 0.78 | SLC6A2 (0.42) | HTR2CHTR6SLC6A4HTR1ASLC6A2 | |
| SCHEMBL4316454 | 0.78 | HTR6 (0.46) | HTR2CHTR6SLC6A4HTR1ASLC6A2 | |
| SCHEMBL4308039 | 0.76 | TSHR (0.48) | HTR2CHTR6SLC6A4TSHRHTR1A | |
| SCHEMBL4324612 | 0.75 | HTR2C (0.48) | HTR2CHTR6SLC6A4TSHRHTR1A | |
| SCHEMBL4326876 | 0.75 | HTR2C (0.48) | HTR2CHTR6SLC6A4TSHRHTR1A | |
| SCHEMBL13116676 | 0.75 | HRH4 (0.44) | HTR2CEPHX2 | |
| SCHEMBL4314317 | 0.75 | NISCH (0.44) | HTR2CSLC6A4HTR1ASLC6A2 | |
| SCHEMBL4314576 | 0.74 | HTR6 (0.48) | HTR2CHTR6SLC6A4ACHEHTR1A | |
| SCHEMBL13116675 | 0.74 | HTR2C (0.42) | HTR2CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |