SCHEMBL7475708

SCHEMBL7475708

CCOC(=O)c1cccc(Br)c1S(N)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
HSD17B10 Q99714 2/20 0.51
ALDH1A1 P00352 1/20 0.51
CA1 P00915 7/20 0.47
CA2 P00918 7/20 0.47
CA12 O43570 6/20 0.47
CA9 Q16790 6/20 0.47
CA7 P43166 3/20 0.47
CA14 Q9ULX7 3/20 0.47
KMT2A Q03164 1/20 0.45
CDC25B P30305 2/20 0.44
STS P08842 1/20 0.43
LMNA P02545 1/20 0.43
CHRNA7 P36544 1/20 0.43
CYP1A2 P05177 1/20 0.42
CDK1 P06493 1/20 0.42
CDK2 P24941 1/20 0.42
KDM4E B2RXH2 1/20 0.42
F2R P25116 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7032677 0.88 ALDH1A1 (0.57) TSHRHSD17B10ALDH1A1KMT2ASTS
SCHEMBL7033343 0.87 TSHR (0.53) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7032319 0.86 TSHR (0.56) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7026000 0.85 TSHR (0.54) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7029300 0.84 TSHR (0.53) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL9139901 0.84 TSHR (0.53) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7031771 0.84 TSHR (0.53) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7469376 0.83 CA1 (0.58) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7034708 0.82 TSHR (0.51) TSHRHSD17B10ALDH1A1CA1CA2
SCHEMBL7030801 0.81 TSHR (0.52) TSHRHSD17B10ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6441195-B1 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
US-6180567-B1 REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed