Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 4/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478103 | 0.90 | TSHR (0.67) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL7483948 | 0.86 | TSHR (0.59) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL9440082 | 0.85 | CARM1 (0.46) | TSHRKMT2AALDH1A1CYP2C19TMEM97 | |
| SCHEMBL7475314 | 0.84 | CARM1 (0.45) | TSHRKMT2AALDH1A1TMEM97CARM1 | |
| SCHEMBL698553 | 0.82 | KMT2A (0.47) | TSHRKMT2AGAAHTTALDH1A1 | |
| Acetic Acid SCHEMBL3797025 | 0.82 | TSHR (0.46) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL7474273 | 0.81 | TSHR (0.44) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL9589452 | 0.81 | TSHR (0.57) | TSHRKMT2AGAAHTTSCN1A | |
| SCHEMBL6812792 | 0.80 | TSHR (0.58) | TSHRKMT2AGAAHTTALDH1A1 | |
| SCHEMBL9243820 | 0.80 | TSHR (0.48) | TSHRKMT2AGAAHTTSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-4921962-A | REACTION OF AMINE WITH HYDROPEROXIDE | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |