SCHEMBL7475314

SCHEMBL7475314

CC1(C)CC(OCc2ccc(COC3CC(C)(C)N(OCc4ccccc4)C(C)(C)C3)cc2)CC(C)(C)N1OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 4/20 0.45
PRMT6 Q96LA8 4/20 0.45
PRMT8 Q9NR22 2/20 0.45
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSK P43235 1/20 0.44
OPRM1 P35372 2/20 0.43
OPRL1 P41146 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 2/20 0.41
KMT2A Q03164 1/20 0.41
NAAA Q02083 4/20 0.40
DPP4 P27487 1/20 0.40
DHFR P00374 2/20 0.37
PRMT3 O60678 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440082 0.98 CARM1 (0.46) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL9240294 0.90 CARM1 (0.44) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL9335197 0.87 CARM1 (0.42) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL17351108 0.86 ALDH1A1 (0.44) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL7476490 0.84 CARM1 (0.36) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL8415341 0.84 CARM1 (0.40) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL7475800 0.84 TSHR (0.53) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL9674864 0.83 CARM1 (0.48) CARM1PRMT6PRMT8TMEM97SIGMAR1
SCHEMBL5062027 0.81 ALDH1A1 (0.45) ALDH1A1TSHRKMT2ADHFR
SCHEMBL13412651 0.81 ALDH1A1 (0.45) CARM1PRMT6PRMT8TMEM97SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US claimed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US claimed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
US-4921962-A REACTION OF AMINE WITH HYDROPEROXIDE CIBA-GEIGY CORPORATION (US) 1990-05-01 US disclosed