Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475985 | 0.94 | GAA (0.49) | GAAGFERPDGFRBPDGFRAAMY1A | |
| SCHEMBL5008296 | 0.84 | GAA (0.66) | GAAPOLBMAPTALDH1A1TDP1 | |
| SCHEMBL7473230 | 0.83 | KDM4E (0.46) | GAAGFERPDGFRBPDGFRAAMY1A | |
| SCHEMBL2272761 | 0.80 | AMY1A (0.50) | AMY1APOLBMAPTALDH1A1TDP1 | |
| SCHEMBL13544185 | 0.78 | MAPT (0.54) | GAAPOLBMAPTALDH1A1TDP1 | |
| SCHEMBL7478904 | 0.78 | GAA (0.51) | GAAPOLBMAPTALDH1A1TDP1 | |
| SCHEMBL2004172 | 0.78 | GAA (0.51) | GAAPOLBMAPTALDH1A1TDP1 | |
| SCHEMBL7473228 | 0.77 | KDM4E (0.46) | GAAGFERPDGFRBPDGFRAAMY1A | |
| SCHEMBL17702668 | 0.77 | AMY1A (0.51) | AMY1APOLBMAPTALDH1A1TDP1 | |
| SCHEMBL25244854 | 0.77 | PDGFRB (0.45) | GFERPDGFRBPDGFRAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-0865281-A4 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0865281-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021437-A1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-06-19 | — | — | WO | disclosed |