Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472588 | 0.85 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL8662299 | 0.84 | HTR1D (0.75) | HTR1DHTR1B | |
| SCHEMBL7474143 | 0.83 | HTR1D (1.00) | HTR1DHTR1B | |
| Dimethylamine SCHEMBL7478598 | 0.82 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL7471977 | 0.82 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL7479541 | 0.80 | HTR1D (0.94) | HTR1DHTR1B | |
| SCHEMBL8663456 | 0.80 | HTR1D (0.68) | HTR1DHTR1B | |
| SCHEMBL8984359 | 0.80 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL7480294 | 0.79 | HTR1D (0.74) | HTR1DHTR1B | |
| SCHEMBL7476780 | 0.79 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |