Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | F7 | P08709 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402998 | 0.90 | F10 (0.58) | KLK1KLK5F2F10F7 | |
| SCHEMBL7476975 | 0.87 | F2 (0.50) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7477294 | 0.86 | APEX1 (0.44) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7478399 | 0.84 | F2 (0.47) | F2F10F7NPC1RAB9A | |
| SCHEMBL7480462 | 0.83 | F10 (0.44) | KLK1KLK5F2F10F7 | |
| SCHEMBL7480797 | 0.83 | F10 (0.47) | KLK1KLK5F2F10F7 | |
| SCHEMBL7479169 | 0.83 | F10 (0.71) | KLK1KLK5F2F10F7 | |
| SCHEMBL7404219 | 0.82 | F10 (0.64) | KLK1KLK5F2F10F7 | |
| SCHEMBL548419 | 0.81 | F10 (0.63) | KLK1KLK5F2F10F7 | |
| SCHEMBL7405159 | 0.79 | F10 (0.55) | KLK1KLK5F2F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |