Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477294 | 0.93 | APEX1 (0.44) | F2APEX1F10TPSAB1PRSS1 | |
| SCHEMBL7476301 | 0.87 | KLK1 (0.53) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7478562 | 0.86 | F10 (0.55) | F2APEX1F10TPSAB1PRSS1 | |
| SCHEMBL7480462 | 0.83 | F10 (0.44) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL23901812 | 0.81 | F2 (0.57) | F2PLGPLAU | |
| SCHEMBL34433937 | 0.81 | F2 (0.57) | F2PLGPLAU | |
| SCHEMBL7409221 | 0.79 | F10 (0.66) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7406196 | 0.79 | F10 (0.56) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL548419 | 0.79 | F10 (0.63) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7405869 | 0.78 | F2 (0.49) | F2F10TPSAB1PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |