Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7464925 | 0.90 | GPR119 (0.42) | GPR119CHIADRD4NPC1RAB9A | |
| SCHEMBL7472329 | 0.90 | GPR119 (0.41) | GPR119CHIADRD4NPC1RAB9A | |
| SCHEMBL7472375 | 0.90 | SMN1; SMN2 (0.42) | GPR119CHIADRD4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7461110 | 0.89 | GPR119 (0.41) | GPR119CHIADRD4NPC1RAB9A | |
| SCHEMBL9393753 | 0.89 | CHIA (0.42) | GPR119CHIADRD4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7471364 | 0.88 | CHIA (0.42) | GPR119CHIADRD4NPC1RAB9A | |
| SCHEMBL7476121 | 0.87 | KMT2A (0.44) | GPR119 | |
| SCHEMBL7469286 | 0.87 | DRD4 (0.40) | GPR119CHIADRD4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7472415 | 0.86 | KMT2A (0.43) | GPR119 | |
| SCHEMBL9393732 | 0.86 | GPR119 (0.39) | GPR119CHIADRD4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |