Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014816 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL1146057 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL6638580 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| Oxalic Acid SCHEMBL7426081 | 0.86 | POLB (0.57) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL8353859 | 0.85 | POLB (0.53) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL6087660 | 0.83 | DPP4 (0.57) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL5099213 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL3941650 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL7363076 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL9143702 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2POLBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002032896-A1 | FURAZANYL-TRIAZOLE DERIVATES FOR THE TREATMENT OF DISEASES | NOVO NORDISK A/S (DK) | 2002-04-25 | — | — | WO | disclosed |