SCHEMBL7476952

SCHEMBL7476952

CCCCNC1CC(C)(C)N(OC(C)c2ccccc2)C(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
SLC2A1 P11166 1/20 0.35
CTSK P43235 8/20 0.35
CTSV O60911 3/20 0.35
CTSL P07711 3/20 0.35
CTSS P25774 3/20 0.35
CTSB P07858 2/20 0.35
MAPT P10636 2/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
POLB P06746 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7475386 0.95 SLC2A1 (0.38) KMT2AALDH1A1GAAHTTMEN1
SCHEMBL13386836 0.77 KMT2A (0.44) KMT2AGAAMEN1CTSKCTSV
SCHEMBL13460343 0.76 TSHR (0.37) KMT2AGAAMEN1
SCHEMBL13474845 0.76 KMT2A (0.43) KMT2AALDH1A1GAAMEN1CTSK
SCHEMBL13474888 0.76 TSHR (0.39) KMT2AALDH1A1GAAMEN1SLC6A2
SCHEMBL19937352 0.76 TSHR (0.39) KMT2AALDH1A1GAAMEN1SLC6A2
SCHEMBL22064475 0.75 KMT2A (0.42) KMT2AALDH1A1GAAMEN1
SCHEMBL28499411 0.75 BCHE (0.40) KMT2AALDH1A1GAAHTTMEN1
SCHEMBL6809943 0.74 KMT2A (0.37) KMT2A
SCHEMBL13008720 0.74 TACR1 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
EP-0389430-B1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5021481-A For use with polymers CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed