SCHEMBL7475386

SCHEMBL7475386

CCCCCCCCCCCCNC1CC(C)(C)N(OC(C)c2ccccc2)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.38
NAAA Q02083 2/20 0.36
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
OPRM1 P35372 2/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
OPRL1 P41146 2/20 0.34
CTSK P43235 5/20 0.34
CTSV O60911 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
MEN1 O00255 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476952 0.95 KMT2A (0.39) SLC2A1KMT2AALDH1A1GAAHTT
SCHEMBL5340971 0.78 NAAA (0.40) NAAAALDH1A1HTT
SCHEMBL22064475 0.78 KMT2A (0.42) NAAAKMT2AALDH1A1GAAMEN1
SCHEMBL13474845 0.76 KMT2A (0.43) NAAAKMT2AALDH1A1GAACTSK
SCHEMBL5345766 0.76 NAAA (0.40) NAAAKMT2A
SCHEMBL13412656 0.76 NPC1 (0.39) HTTCNR1CNR2
SCHEMBL14590867 0.75 ASAH1 (0.42) KMT2AALDH1A1HTTMEN1CNR1
SCHEMBL14590870 0.75 ASAH1 (0.42) KMT2AALDH1A1HTTMEN1CNR1
SCHEMBL14590866 0.75 ASAH1 (0.42) KMT2AALDH1A1HTTMEN1CNR1
SCHEMBL6322078 0.75 ASAH1 (0.42) KMT2AALDH1A1HTTMEN1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
EP-0389430-B1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5021481-A For use with polymers CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed