Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389985 | 0.96 | ITGA4 (0.57) | ITGA4ITGB1CHEK1WNT3A | |
| SCHEMBL7381056 | 0.94 | ITGA4 (0.57) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7420868 | 0.93 | ITGA4 (0.61) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7429378 | 0.91 | ITGA4 (0.59) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7429626 | 0.91 | ITGB1 (0.59) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7421482 | 0.90 | ITGB1 (0.55) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7419416 | 0.90 | ITGA4 (0.55) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7421315 | 0.89 | ITGB1 (0.57) | ITGA4ITGB1CHEK1WNT3A | |
| SCHEMBL7648845 | 0.88 | ITGA4 (0.54) | ITGA4ITGB1CHEK1MEN1KMT2A | |
| SCHEMBL7588952 | 0.88 | ITGA4 (0.60) | ITGA4ITGB1CHEK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |