Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489169 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL15546828 | 0.80 | LOXL2 (0.30) | — | |
| SCHEMBL28224988 | 0.69 | — | — | |
| SCHEMBL10031673 | 0.68 | — | — | |
| SCHEMBL22181784 | 0.68 | — | — | |
| SCHEMBL23233734 | 0.68 | — | — | |
| SCHEMBL12962901 | 0.68 | — | — | |
| SCHEMBL6290262 | 0.65 | CFTR (0.35) | — | |
| SCHEMBL14398442 | 0.64 | PTPN22 (0.37) | — | |
| SCHEMBL3911165 | 0.63 | PTPN22 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222174-A1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | Takeda Chemical Industries, Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001030762-A1 | IMIDAZOL-4-YLMETHANOLS USE AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |