Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.78 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478383 | 0.97 | F10 (0.76) | F10PRSS1 | |
| SCHEMBL14132262 | 0.88 | F10 (1.00) | F10PRSS1F2 | |
| SCHEMBL14132003 | 0.87 | F10 (0.98) | F10PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL3901365 | 0.84 | F10 (0.89) | F10PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL5105095 | 0.84 | F10 (0.87) | F10PRSS1F2 | |
| SCHEMBL7475225 | 0.83 | F10 (1.00) | F10PRSS1 | |
| SCHEMBL7471700 | 0.82 | F10 (1.00) | F10PRSS1 | |
| SCHEMBL7475473 | 0.81 | F10 (1.00) | F10PRSS1F2 | |
| SCHEMBL3901372 | 0.80 | F10 (0.64) | F10PRSS1 | |
| SCHEMBL5105097 | 0.79 | F10 (0.62) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |