Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471700 | 0.99 | F10 (1.00) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7475473 | 0.98 | F10 (1.00) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7476367 | 0.91 | F10 (0.83) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7479884 | 0.91 | F10 (1.00) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7484452 | 0.90 | F10 (1.00) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7477445 | 0.83 | F10 (0.71) | F10PRSS1LMNAMAPTHTT | |
| SCHEMBL7477366 | 0.83 | F10 (0.78) | F10PRSS1 | |
| SCHEMBL7482442 | 0.83 | F10 (1.00) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7479235 | 0.83 | F10 (0.70) | F10PRSS1ALDH1A1LMNAMAPT | |
| SCHEMBL7478383 | 0.82 | F10 (0.76) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |