Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477373 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKDM4EGAATHRB | |
| SCHEMBL6835113 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL6835112 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL10717796 | 0.85 | CYP1A2 (0.50) | SMN1; SMN2MAPTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL11277749 | 0.81 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL7474653 | 0.81 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL7474656 | 0.81 | CYP1A2 (0.39) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL7471412 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTKDM4EGAATHRB | |
| SCHEMBL7471414 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTKDM4EGAATHRB | |
| SCHEMBL5847912 | 0.79 | CYP1A2 (0.35) | CYP1A2CYP2C19ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |