Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477902 | 0.89 | GRM2 (0.64) | GRM2DRD4ALDH1A1KDM4ETSHR | |
| SCHEMBL7475139 | 0.87 | GRM2 (0.62) | GRM2DRD4ALDH1A1KDM4ENPSR1 | |
| SCHEMBL7475105 | 0.85 | GRM2 (0.43) | GRM2DRD4KDM4EPOLBLMNA | |
| SCHEMBL7474510 | 0.83 | KDM4E (0.48) | GRM2DRD4KDM4EPOLBTSHR | |
| SCHEMBL7477326 | 0.83 | MEN1 (0.52) | GRM2DRD4ALDH1A1KDM4EPOLB | |
| SCHEMBL7474146 | 0.83 | HPGD (0.59) | GRM2ALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL7473319 | 0.83 | GRM2 (0.51) | GRM2DRD4ALDH1A1KDM4EPOLB | |
| SCHEMBL7477431 | 0.82 | KDM4E (0.45) | DRD4ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL7471278 | 0.81 | KDM4E (0.58) | GRM2DRD4ALDH1A1KDM4EPOLB | |
| SCHEMBL7477813 | 0.81 | KDM4E (0.49) | GRM2DRD4KDM4ENPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | claimed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | claimed |
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |