Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22347081 | 0.91 | KDM4E (0.47) | GPR119KDM4EPKMEPHX1NPC1 | |
| SCHEMBL7390308 | 0.86 | KDM4E (0.46) | GPR119KDM4EPKMEPHX1ALDH1A1 | |
| SCHEMBL7390703 | 0.84 | EPHX1 (0.45) | GPR119KDM4EPKMEPHX1HPGD | |
| SCHEMBL9407985 | 0.83 | KDM4E (0.52) | GPR119KDM4EPKMEPHX1HPGD | |
| SCHEMBL7391575 | 0.82 | KDM4E (0.49) | GPR119KDM4EPKMEPHX1HPGD | |
| SCHEMBL1575153 | 0.82 | HPGD (0.49) | GPR119KDM4EPKMEPHX1NPC1 | |
| SCHEMBL1842334 | 0.82 | HPGD (0.49) | GPR119KDM4EPKMEPHX1NPC1 | |
| SCHEMBL26637947 | 0.82 | HPGD (0.49) | GPR119KDM4EPKMEPHX1NPC1 | |
| SCHEMBL30670131 | 0.82 | HPGD (0.49) | GPR119KDM4EPKMEPHX1NPC1 | |
| SCHEMBL15864288 | 0.81 | KDM4E (0.55) | GPR119KDM4EPKMNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |