Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224989 | 0.88 | GPR119 (0.53) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL4426117 | 0.88 | KDM4E (0.55) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL2959700 | 0.86 | KDM4E (0.51) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL3132960 | 0.85 | HPGD (0.54) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL4012248 | 0.85 | KDM4E (0.53) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL16014055 | 0.85 | KDM4E (0.53) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL7391575 | 0.84 | KDM4E (0.49) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL15085741 | 0.83 | GPR119 (0.59) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL7478046 | 0.83 | GPR119 (0.47) | KDM4EPKMEPHX1GPR119HPGD | |
| SCHEMBL310405 | 0.82 | HPGD (0.54) | KDM4EPKMEPHX1GPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |