Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478183 | 1.00 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL7478172 | 1.00 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL7466471 | 0.89 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9128455 | 0.87 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL7534642 | 0.86 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL7534650 | 0.86 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL7534645 | 0.86 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9126565 | 0.86 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9131755 | 0.86 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9127767 | 0.86 | ALOX5 (0.47) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |