Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696714 | 0.83 | HTR1D (0.47) | HTR1DHTR1B | |
| SCHEMBL7475880 | 0.78 | HTR1D (0.83) | HTR1DHTR1B | |
| SCHEMBL4340068 | 0.78 | HTR1D (1.00) | HTR1DHTR1B | |
| Oxalic Acid SCHEMBL8662945 | 0.78 | HTR1D (0.91) | HTR1DHTR1B | |
| SCHEMBL8177129 | 0.77 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL8662011 | 0.76 | HTR1D (0.82) | HTR1DHTR1B | |
| SCHEMBL4352154 | 0.76 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8657524 | 0.75 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL7475895 | 0.75 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL4340558 | 0.75 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6051572-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME LTD. (GB) | 2000-04-18 | — | — | US | disclosed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1997016445-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-09 | — | — | WO | disclosed |