Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.37 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | KHK | P50053 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478455 | 1.00 | F10 (0.37) | F10F2KHKPRSS1OPRM1 | |
| SCHEMBL7476624 | 0.96 | F10 (0.36) | F10F2KHKPRSS1OPRM1 | |
| SCHEMBL7476632 | 0.96 | F10 (0.36) | F10F2KHKPRSS1OPRM1 | |
| Hydrochloric Acid SCHEMBL7480546 | 0.87 | F10 (0.38) | F10F2KHKPRSS1CYP17A1 | |
| Hydrochloric Acid SCHEMBL7475209 | 0.84 | KDM4E (0.38) | F10F2KHKPRSS1CYP17A1 | |
| SCHEMBL7467625 | 0.84 | F10 (0.37) | F10F2KHKPRSS1HRH3 | |
| SCHEMBL7465362 | 0.82 | F10 (0.37) | F10F2KHKPRSS1CYP17A1 | |
| SCHEMBL7479561 | 0.81 | RORC (0.39) | F10F2KHKPRSS1 | |
| Hydrochloric Acid SCHEMBL7559934 | 0.81 | F2 (0.34) | F10F2KHKPRSS1CYP17A1 | |
| SCHEMBL7481467 | 0.81 | F10 (0.35) | F10F2KHKPRSS1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |