Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475254 | 0.91 | HSD17B10 (0.46) | KMT2AMEN1MAPTMAPK1HTT | |
| SCHEMBL7468823 | 0.86 | BRD4 (0.45) | KMT2AMEN1BRD4HSD17B10ALDH1A1 | |
| SCHEMBL7468480 | 0.85 | BRD4 (0.42) | KMT2AMEN1MAPTMAPK1BRD4 | |
| SCHEMBL7471027 | 0.82 | KMT2A (0.60) | KMT2AMEN1MAPTMAPK1BRD4 | |
| SCHEMBL7472416 | 0.82 | PARP1 (0.48) | KMT2AMEN1MAPTMAPK1HSD17B10 | |
| SCHEMBL7460760 | 0.81 | L3MBTL1 (0.53) | KMT2AMEN1MAPTMAPK1BRD4 | |
| SCHEMBL7470585 | 0.79 | USP2 (0.56) | KMT2AMEN1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL7463453 | 0.78 | HSD17B10 (0.48) | KMT2AMEN1MAPTMAPK1HSD17B10 | |
| SCHEMBL7472662 | 0.78 | L3MBTL1 (0.43) | KMT2AMEN1MAPK1BRD4HSD17B10 | |
| SCHEMBL5802317 | 0.78 | L3MBTL1 (0.43) | KMT2AMEN1MAPK1BRD4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |