SCHEMBL747849

SCHEMBL747849

COc1ccc(C(=O)c2ccccc2C(C)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.68
NPC1 O15118 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
NPSR1 Q6W5P4 3/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 1/20 0.55
CES2 O00748 2/20 0.55
CES1 P23141 2/20 0.55
MAPT P10636 4/20 0.53
LMNA P02545 3/20 0.53
HPGD P15428 3/20 0.53
RAB9A P51151 3/20 0.53
MAPK1 P28482 2/20 0.53
MEN1 O00255 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
HTT P42858 2/20 0.53
CYP1A2 P05177 1/20 0.53
PGR P06401 1/20 0.53
CYP2D6 P10635 1/20 0.53
SLC6A2 P23975 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1375270 0.86 KMT2A (0.68) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL238088 0.86 KMT2A (0.68) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL9205238 0.84 NPC1 (0.68) KMT2ANPC1NPSR1ALDH1A1MAPT
SCHEMBL9712341 0.84 KMT2A (0.71) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL11842420 0.84 KMT2A (0.66) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL9851196 0.84 KMT2A (0.70) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL7145045 0.83 KMT2A (0.64) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
P-Anisic Acid SCHEMBL3660840 0.83 CA1 (0.67) KMT2ASMN1; SMN2ALDH1A1TP53CES2
SCHEMBL7145069 0.83 KMT2A (0.64) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1
SCHEMBL231448 0.82 KMT2A (0.68) KMT2ANPC1SMN1; SMN2NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372907-B2 Stabilizer for chlorine-containing resins and chlorine-containing resin composition ADEKA CORPORATION (JP) 2013-02-12 US claimed
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION AKDENIZ CHEMSON ADDITIVES A.G. (AT) 2026-05-28 US disclosed
EP-4745191-A1 POLYVINYL CHLORIDE-BASED RESIN COMPOSITION, AND FILM PRODUCED THEREFROM Riken Technos Corporation (JP) 2026-05-20 EP disclosed
CN-120076911-A Method and device for producing a stabilizer composition in particulate form and stabilizer composition produced thereby 阿登尼斯开米森添加剂股份公司 2025-05-30 CN disclosed
US-20250129206-A1 POLYESTER-BASED PLASTICIZER, VINYL CHLORIDE-BASED RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2025-04-24 US disclosed
WO-2025018141-A1 POLYVINYL CHLORIDE-BASED RESIN COMPOSITION, AND FILM PRODUCED THEREFROM リケンテクノス株式会社 2025-01-23 WO disclosed
WO-2024256407-A1 METHOD FOR TREATING HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2024-12-19 WO disclosed
EP-4477694-A1 METHOD FOR TREATING HALOGENATED POLYMERS Baerlocher GmbH (DE) 2024-12-18 EP disclosed
EP-4397690-A1 POLYESTER-BASED PLASTICIZER, VINYL CHLORIDE-BASED RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2024-07-10 EP disclosed
US-20240165866-A1 METHOD FOR PRODUCING A STABILISER COMPOSITION FOR A POLYMER, AND STABILISER COMPOSITION PRODUCED USING SAID METHOD AKDENIZ CHEMSON ADDITIVES AG (AT) 2024-05-23 US disclosed
US-5252645-A Additives of hydrotacite, perchlorate-containing hydrotalcite, a beta-diketone, a carboxylic acid salt and an organic tin compound KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1993-10-12 US disclosed
US-5244949-A Light and heat CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
EP-0489545-A1 Antistatic, thermally stabilized halogen-containing resin composition KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1992-06-10 EP disclosed
US-4751261-A CONTAINING MAGNESIUM OXIDE, HYDROTALCITE, DIKETONE AND ORGANIC ZINC SALT KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1988-06-14 US disclosed
EP-0256872-A2 Stabilized polyvinyl chloride resin composition KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1988-02-24 EP disclosed
US-4675356-A HYDROTALCITE SOLID SOLUTION KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1987-06-23 US disclosed
EP-0063180-B1 BETA-DIKETONE AND HYDROTALCITE STABILIZER COMPOSITIONS FOR HALOGEN-CONTAINING POLYMERS AND POLYMER COMPOSITIONS CONTAINING THE SAME ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-04-08 EP disclosed
EP-0189899-A2 Synthetic resin composition having reduced corrosion-causing tendency and coloration Kyowa Chemical Industry Co., Ltd. (JP) 1986-08-06 EP disclosed
US-4427816-A β-Diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1984-01-24 US disclosed
EP-0063180-A1 Beta-diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION GRN, IL36G, GMNN KMT2A 4384/4885NPC1 1816/4885SMN1; SMN2 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.