Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479831 | 0.81 | MEN1 (0.42) | GAAMEN1KMT2AMAPTTDP1 | |
| SCHEMBL7966716 | 0.77 | PKN1 (0.55) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL7478049 | 0.71 | PKN1 (0.48) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL1013588 | 0.71 | PKN1 (0.60) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL1548768 | 0.70 | ALDH1A1 (0.43) | GAAPDE10AMEN1KMT2AALDH1A1 | |
| SCHEMBL8599658 | 0.70 | PKN1 (0.56) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL7475814 | 0.70 | PKN1 (0.47) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL18776090 | 0.70 | PKN1 (0.52) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL6332531 | 0.69 | PKN1 (0.61) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL7475180 | 0.69 | PKN1 (0.51) | PKN1PKN2ADORA3MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |