Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.53 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409221 | 0.92 | F10 (0.66) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548419 | 0.92 | F10 (0.63) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL11887806 | 0.90 | APEX1 (0.64) | APEX1NPSR1ALDH1A1MAPK1 | |
| SCHEMBL7479757 | 0.88 | APEX1 (0.60) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7476975 | 0.86 | F2 (0.50) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548407 | 0.86 | F10 (0.60) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7477294 | 0.85 | APEX1 (0.44) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7479169 | 0.85 | F10 (0.71) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7407065 | 0.85 | F10 (0.56) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7485743 | 0.85 | F10 (0.52) | F10TPSAB1PRSS1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | claimed |
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |