SCHEMBL7478640

SCHEMBL7478640

CC[C@]1(CO)CS(=O)(=O)c2ccccc2[C@H](c2ccccc2)N1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8203749 0.92 SLC10A2 (0.81) SLC10A2
SCHEMBL13334949 0.88 SLC10A2 (0.86) SLC10A2
SCHEMBL8379990 0.88 SLC10A2 (0.86) SLC10A2
SCHEMBL7480380 0.87 SLC10A2 (0.81) SLC10A2
SCHEMBL7485850 0.87 SLC10A2 (0.81) SLC10A2
Hydrochloric Acid SCHEMBL8380609 0.86 SLC10A2 (0.84) SLC10A2
Hydrochloric Acid SCHEMBL7478839 0.86 SLC10A2 (0.80) SLC10A2
SCHEMBL8799406 0.86 SLC10A2 (0.69) SLC10A2
SCHEMBL349300 0.85 SLC10A2 (1.00) SLC10A2
SCHEMBL8691592 0.85 SLC10A2 (0.71) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683774-B1 HYPOLIPIDAEMIC COMPOUNDS WELLCOME FOUND (GB) 2002-10-09 EP disclosed
US-5817652-A ATHEROSCLEROSIS GLAXO WELLCOME INC. (US) 1998-10-06 US disclosed
US-5723458-A 1,4-BENZOTHIAZEPINES GLAXO WELLCOME INC. (US) 1998-03-03 US disclosed
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP disclosed
EP-0683774-A1 HYPOLIPIDAEMIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1995-11-29 EP disclosed
WO-1994018184-A1 HYPOLIPIDAEMIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO disclosed