Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12368426 | 0.84 | ALDH1A1 (0.65) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL13922754 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL11352597 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL6941062 | 0.81 | CACNA1B (0.62) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL5508324 | 0.81 | ALDH1A1 (0.70) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL13210697 | 0.81 | CACNA1B (0.85) | ALDH1A1CACNA1BAPBA1SMN1; SMN2POLB | |
| SCHEMBL2924725 | 0.79 | CACNA1B (0.65) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL10755434 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL5507897 | 0.79 | SMN1; SMN2 (0.61) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 | |
| SCHEMBL11196763 | 0.79 | ALDH1A1 (0.64) | ALDH1A1NFKB1KCNH2CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | claimed |
| EP-0742903-B1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-0742903-A4 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0742903-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5525474-A | IMMUNOASSAY; LINKING THE HAPTENIC DRUG VIA ITS MALEIMIDE MOIETY AND A SULFHYDRYL BRIDGE TO AN IMMUNOGENIC CARRIER TO STIMULATE ANTIBODIES | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995020763-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1995-08-03 | — | — | WO | disclosed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |