SCHEMBL7478919

SCHEMBL7478919

CCCC[C@@]1(CC)CSc2ccc(OC(C)C)cc2[C@H](c2ccccc2)N1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7478924 1.00 SLC10A2 (0.45) SLC10A2
SCHEMBL14678602 0.92 SLC10A2 (0.45) SLC10A2
SCHEMBL8223309 0.92 SLC10A2 (0.45) SLC10A2
SCHEMBL8223308 0.92 SLC10A2 (0.45) SLC10A2
SCHEMBL8239487 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8200621 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8239482 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8380393 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8380396 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8381546 0.83 SLC10A2 (0.49) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683774-B1 HYPOLIPIDAEMIC COMPOUNDS WELLCOME FOUND (GB) 2002-10-09 EP disclosed
US-5723458-A 1,4-BENZOTHIAZEPINES GLAXO WELLCOME INC. (US) 1998-03-03 US disclosed