Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785384 | 0.86 | TP53 (0.49) | PNMTTSHRTP53SIGMAR1ALDH1A1 | |
| SCHEMBL7969292 | 0.84 | TSHR (0.47) | PNMTTSHRTP53KMT2AMEN1 | |
| SCHEMBL5236913 | 0.81 | PNMT (0.54) | PNMTTSHRTP53IDO1SIGMAR1 | |
| SCHEMBL26210601 | 0.79 | TP53 (0.61) | TSHRTP53IDO1KMT2AMEN1 | |
| SCHEMBL7621904 | 0.79 | TP53 (0.61) | TSHRTP53IDO1KMT2AMEN1 | |
| SCHEMBL5018935 | 0.78 | PNMT (0.70) | PNMTTSHRTP53IDO1SIGMAR1 | |
| SCHEMBL1150544 | 0.78 | PNMT (0.50) | PNMTTSHRIDO1SIGMAR1TAAR1 | |
| SCHEMBL21700144 | 0.78 | PNMT (0.59) | PNMTTSHRIDO1SIGMAR1TAAR1 | |
| SCHEMBL10078145 | 0.78 | PNMT (0.59) | PNMTTSHRIDO1SIGMAR1TAAR1 | |
| SCHEMBL15213093 | 0.77 | PNMT (0.50) | PNMTTSHRIDO1SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756596-A1 | TROPANE-2-ALDOXIME DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995028401-A1 | TROPANE-2-ALDOXINE DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1995-10-26 | — | — | WO | disclosed |